Last Updated on April 19, 2026 by Eve Dawes
Does Dr Jason Diamond’s Metacine Instafacial live up to it’s anti-aging skincare promises as a luxury skincare routine that defies time?
Dr Diamond’s Metacine collection is an ever evolving luxury skincare routine but does it work? At this price point you’ve got to hope the Metacine Plasma Growth Factor Serum, Infusion, Emulsion retinoid night cream, HYDR/O Bioactive Hydrolipid Barrier and Eyelift would give dramatic results. After all, it’s formulated by top Beverly Hills Facial Plastic Surgeon Dr Jason Diamond and inspired by his in-office procedure, the Diamond InstaFacial. The famous Instafacial features a series of lasers & PRP micro needling and the Metacine Instafacial is designed to give you similar results at home. Or at least the best we can hope for without having professional lasers and microneedling machines at home! It’s a lot to fork out, so here’s an honest review on the plasma, infusion, emulsion, HYDR/O, Eyelift, how to use them, tips, benefits, before and after photos, results and whether I think it’s worth it or not in this Dr Diamond’s Metacine review.
I’ve been using Dr Diamond’s Metacine InstaFacial collection since it launched and have tested each product as it was added to the line, giving me a longer-term perspective on results than most reviews offer. I also attended an exclusive Zoom masterclass with Dr Jason Diamond himself on the launch of the new Eyelift, which means my coverage of that product comes directly from the source. I bring professional beauty formulation training through my own cosmetics line, Dawes Custom Cosmetics, which informs how I analyse ingredients and clinical claims in every product I review. Before and after photos included throughout. This article contains affiliate links which do not affect my opinion or the price.
Who is Dr. Jason Diamond
Dr. Jason Diamond is the famous plastic surgeon and facial specialist whose celebrity clients include Katy Perry, the Kardashians and Chrissy Teigen. Dr. Jason Diamond is renowned for his facial surgeries and Diamond InstaFacial, the price of which varies depending on what treatments are necessary and isn’t listed, but you can expect to be eye watering. Luckily Dr. Diamond’s Metacine is inspired by his Diamond Instafacial and designed to give us similar results for a lot less at home.
What is the Metacine Instafacial Collection
Dr Diamonds Metacine is the pricey, what was a two-step luxury skincare system that’s now a 5 step system, you’ve probably seen all over Instagram. Formulated with most state of the art, high tech ingredients on the forefront of skincare science. Metacine’s ingredients are touted to mimic our body’s own cell signaling molecules to generate collagen, elastin & hyaluronic acid production but does it work?
Dr Diamond Metacine Plasma mimics what’s used in his Instafacial and has human growth factors. The Emulsion is touted as laser treatment in a bottle. It exfoliates with a unique retinoid that is safe to use all year even on sensitive skin (with no irritation). The Instafacial Infusion serum is designed to firm, lift and tighten. HYDR/O Bioactive Hydrolipid Barrier is a hydrating moisturizer and Eyelift is designed to tackle all 10 signs of aging on both the upper lids and under eyes.
Is Dr Jason Diamond’s Beverly Hills skincare worth it?
Firstly let’s look at the ingredients in Dr Diamond skincare which are the main reason for it’s high price point. The Instafacial Collection is a state of the art 4-step system formulated with 31 bioactive ingredients in the Plasma and Emulsion designed to accelerate skin rejuvenation, support collagen, elastin and hyaluronic acid production to visibly smooth, lift and firm for a tighter, more youthful look with clinically proven results.
Their clinical trials show:
- 91% Improvement in crow’s feet wrinkles
- 77% Improvement in under-eye elasticity
- 91% Smoother & more refined skin texture
- 82% Healthier & more youthful skin
- 91% Firmer & lifted skin
- 82% More luminous & radiant skin
That’s all well and good in theory but let’s look at the results.
Step 1: Dr. Diamond’s Metacine InstaFacial Collection review | Dr. Diamond Metacine Plasma $200
Dr Diamond’s Metacine Instafacial Plasma mimics what’s used in Dr. Diamond’s Instafacial and has 5 bioengineered, bioidentical human growth factors. These are designed to simulate the effect of platelet-rich plasma to support skin repair and rejuvenation by turning on production of collagen, elastin and hyaluronic acid.
It also has potent anti-inflammatory peptides that are supposed to function similarly to Botox, diminishing the look of expression lines & possibly prolonging the effects of Botox, their words not mine, and support wound healing.
It can also be used in place of vitamin C but I don’t personally normally use Vitamin C.
Step 2: NEW Dr Diamond’s Metacine EyeLift Bioremodeling Peptide Multiplex $225
Dr Diamond has just launched the EyeLift, the newest addition to the Metacine collection and the first product in his new Contour Collection, inspired by his non-surgical Diamond Facial Contour procedures. I attended an exclusive Zoom masterclass with Dr Diamond on the launch and have been testing it since release.
It’s a clinically validated bioserum targeting 10 signs of aging around both the under-eye and upper lid: puffiness, dark circles, fine lines, wrinkles, loss of firmness, loss of volume, poor contour definition and upper lid laxity. The Bioremodeling Peptide Complex uses bioengineered human-identical peptides to support structural protein production while inhibiting collagen breakdown simultaneously.
To use: Apply 1 pump morning and evening after your Plasma and before Infusion. It’s hydrating, absorbs quickly and wears well under makeup as long as you don’t overapply. One pump across both eyes is plenty.
For my full review, masterclass insights from Dr Diamond and longer-term before and after results, read my dedicated Dr Diamond’s Eyelift review.
Shop the EyeLift – $225
Step 3: Metacine Instafacial Infusion Biomimetic Microcollagen Matrix $350
Metacine Instafacial Infusion Biomimetic Microcollagen Matrix was designed as the ultimate science-backed solution for gravity-defying skin. This lightweight creamy gel collagen treatment is step 3 in the InstaFacial® Collection. Formulated with a proprietary matrix of three types of bioengineered, human-identical microcollagen, engineered in a lab to be human-identical to make it more stable, consistent and potent, that claims to visibly firm, lift, contour & hydrate your skin.
You apply 1-2 pumps on slightly damp skin both in the morning and evening after your Instafacial Plasma and Eyelift in the morning and in the evening.
I just got mine on Valentine’s Day and the bottle lasted me 2 months when using it twice a day. It had outstanding results in their clinical trials and I’m sharing my personal before and after results below.
Step 4: Dr Diamond’s Metacine collection review | Metacine Instafacial Emulsion Retinopro Growth Factor Night Cream $350
Metacine Instafacial Emulsion is designed to be like a laser treatment in a bottle. It’s a direct-acting, non-irritating bioactive retinoid night cream exfoliates with a unique retinoid that is safe to use all year even on sensitive skin, they say with no irritation and it hasn’t irritated my skin at all. You also don’t have to give up this retinoid for Summer, just make sure to only use it at night.
It also has potent peptides, lipopeptides, a human identical growth factor, Niacinamide and a 4-molecular weight hyaluronic acid complex. All of these ingredients work together to accelerate cell renewal, supporting collagen, elastin and hyaluronic acid production while hydrating skin and maintaining your skins epidermal barrier. It also allows the plasma to work more effectively thanks to it’s molecular synergy to rejuvenate skin.
INSTAFACIAL EMULSION KEY BENEFITS:
- Supports healthy collagen & elastin.
- Visibly smoothes, lifts and firms.
- Rejuvenates skin for a more youthful appearance.
You only use the Metacine Emulsion at night so it does last about 2 months. It’s applied immediately after the plasma. If you find it causes any dryness, build up to nightly use, and use their HYDR/O in the morning and evening as the last step (before SPF) to help combat any dryness.
Step 5: Dr Diamond’s Metacine Hydr/o Bioactive Hydrolipid Barrier $300
The Hydr/o Bioactive Hydrolipid Barrier is the latest launch from Dr. Diamond’s Metacine skincare line and I got to try it ahead of its release.
It’s their fourth product in the collection and I like that they focus on quality over quantity. They only release one product at a time, and each one goes through extensive research and clinical testing before making it to our shelves.
So what makes this different from just another luxury moisturizer? The Hydr/o Bioactive Hydrolipid Barrier is designed to go deeper than surface-level hydration. It uses a patent-pending technology they call Bioactive Hydrolipid Fusion. Which is a blend of lipid and water micromolecules that closely mimics the way youthful skin hydrates and protects itself. It’s light, absorbs quickly, leaves no greasy residue but still feels rich, nourishing and left my skin feeling really silky and bouncy.
Think of it as both your moisturizer and barrier repair treatment in one. It’s brilliant if you have any dryness from using Metacine Emulsion.
Hydr/o Bioactive Hydrolipid Barrier benefits:
- Delivers deep hydration through multiple layers of the skin.
- Helps repair and strengthen the skin barrier.
- Protects against environmental stressors (like UV + pollution)
- Supports your skin’s microbiome.
- Soothes redness and inflammation.
- Improves texture, elasticity and softness.
If you’re into science-backed skincare, and want hydration that feels like it’s actually doing something, this might be one to watch or add to your Metacine collection.
How to use Metacine Instafacial collection: anti-aging skincare routine
Dr Diamond’s Metacine is a 4 step morning routine and 5 step evening routine:
Morning skincare routine:
- Apply 3-5 drops of the Plasma Growth Factor Serum.
Pro tip: Don’t use a full pipette of the plasma. 3-5 drops is all you need and it will help it to last longer. I made the mistake of using a full dropper each time and it only lasted me 3 weeks whereas I still had plenty of Emulsion left. - Apply 1 pump of Eyelift to both your upper lid and under your eyes.
- Apply 1-2 drops of the Metacine Instafacial Infusion Biomimetic Microcollagen Matrix immediately after the Plasma (to slightly damp skin).
- Apply Hydr/o Bioactive Hydrolipid Barrier before your SPF. In the morning I follow with eye cream (optional) and SPF (a must have as the emulsion contains retinoid).
Evening skincare routine:
- Apply 3-5 drops of the Plasma.
- Apply 1 pump of Eyelift to both your upper lid and under your eyes.
- Apply 1-2 drops of the Metacine Instafacial Infusion Biomimetic Microcollagen Matrix to slightly damp skin.
- Apply 1-2 pumps of the Emulsion Retinoid Night Cream immediately after.
- Apply Hydr/o Bioactive Hydrolipid Barrier.
You could just use this skincare collection for a special occasion but it really is something that’s better to stick to for the long term. As it was really after 8 weeks in their clinical trials that people started to see the difference in firmness and less wrinkles and the best results can take up to 3 months.
Pro tip for using Dr. Diamond Metacine Plasma
To get the best results from your Dr. Diamond Metacine Plasma, try using it after your next at-home microneedling treatment. The micro channels you create during your treatment will allow the plasma to penetrate even deeper. Allowing the human growth factors regenerating and healing properties in the plasma to work optimally.
The NEW Metacine Instafacial 5 step system review
The Metacine Instafacial collection just went from 2 steps to 5 steps which originally I wasn’t happy about because of the increase in cost, but to be fair what luxury skincare system isn’t costly. I loved the original concept of it decluttering and streamlining your skincare routine into 2 steps but adding another few steps does push up the price of this skincare system from $550 to $1400 (Instafacial Trio + Eyelift + HYDR/O Bioactive Hydrolipid Barrier) and negates it being what it once was, a streamlined skincare routine. However…
If you already love the system and aren’t bothered by the price tag obviously you’re going to get a lot more benefits from using the full Dr Diamond’s Metacine collection than just the original 2. And I did feel like this collection could benefit from a deeply hydrating moisturizer which is the HYDR/O Bioactive Hydrolipid Barrier ($300) that mimics youthful skin’s ability to hydrate, repair & protect itself.
All of Dr. Diamond’s Metacine collection is designed to work synergistically and in harmony with your skin to visibly lift, firm and hydrate your skin for immediate & long-term results.
Skin that looks and feels firmer, lifted, hydrated and defined. Metacine
Is Dr Diamond Metacine worth it?
There’s no getting around the fact that it’s expensive and now even more so if you add in the Eyelift. Can you personally justify the cost? It depends on whether you see enough results to make it worth it. Can you streamline your skincare routine as that will save you some money? How much do you normally spend on skincare? If you normally buy drugstore brands I’m not going to tell you to rush out and buy this luxury skincare collection but if it’s in your price range it’s a phenomenal option. Dr Diamond’s Metacine collection has:
- Powerful ingredients. I got through my 1st Instafacial collection quickly as I was using way too much. Now I just use 3 drops of the Plasma and 1-2 pumps of the Emulsion so it lasts at least 2 months.
- It can minimize the amount of other products used and skincare steps: Now this was more relevant when it was 2 products and not 5. However, you don’t need to use a Vitamin C, serum, moisturizer, oil, or eye cream with these and they’re safe to use around your eyes. The collection is designed to replace everything but your sunscreen (and you can still use retinol if you prefer). I manage without my other products when I travel but when I’m home in Vegas I do still use an eye cream.
- Effectiveness: You should see glowing, hydrated skin within days. Clinical trial results showed that 91% of people reported smoother, more refined skin after 4 weeks and 91% saw an improvement in crow’s feet at 8 weeks. So be patient with it. My before and after results below speak for themselves.
Dr Diamond’s Metacine before and after photos and results
2026 updates on using the full Dr Diamond’s Metacine Insfacial below. I’ve been using the 2 step system every morning and evening for 2 months now and these are my results. It’s not a miracle fix or face lift in a bottle but there are definite improvements. Even my friends started complimenting me on my skin and asked what I was doing, as they know as a Beauty Editor I’m always trying something new.
I highly recommend taking before and after photos so you can track your progress. As it’s very hard to track progress just by looking in the mirror day after day as the results don’t come overnight.
Results after 1 month using Dr Diamond skincare:
The biggest changes I saw were that my pores looked a lot smaller and less visible, there was improvement in my overall skin tone and radiance, reduction in brown hyperpigmentation spots, and my skin color looked more even.
Dr Diamond Metacine before and after results using the 3 step system
After seeing my Dr Diamond Metacine before and after results using the 2 step system, I was even more excited to put the 3 step system to the test to see what my results would be like. These are my results after using the Plasma and Infusion in the morning and Plasma, Infusion and Emulsion in the evening every day for 5 weeks.
What I notice the most is the softening of my fine lines on my forehead, around my eyes and my smile lines, my pores look smaller, the texture looks more refined and my sun spots appear lighter. Pretty amazing results for only 5 weeks use!
Dr Diamond’s Metacine Instafacial Collection before and after results using the full collection
I just started using Eyelift so will update this after 6 weeks to show my before and after results using it with the Plasma.
Shop Dr Diamond Metacine Instafacial collection
If you’re wanting to try Dr Diamond’s Metacine Instafacial collection before committing to the full size products, you can buy miniature size versions to give it a go. At under $100, it’s a more affordable way to try the collection or to travel with if you’re doing carry-on only, or want to save space.
To save money, you can save 10% by choosing Automatic Refill when you’re purchasing.
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